WebApr 4, 2024 · Aconitate decarboxylase 1 suppresses cerebral ischemia-reperfusion injury in mice. The crystal structure of mouse IRG1 suggests that cis-aconitate decarboxylase has an open and closed conformation. this study shows that ZBP1 and RIPK3 induce IRG1 to promote an antiviral metabolic state in neurons WebJul 24, 2024 · This complex enables the direct delivery of IRG1's antimicrobial product, itaconate, from the mitochondria to Salmonella -containing vacuoles. Itaconate concentrations in vacuoles correlated with bacterial survival, highlighting the biological relevance of this metabolite during infections.
Recombinant Anti-IRG1 antibody [EPR22066] (ab222411) Abcam
WebJul 1, 2024 · We examined that the mRNA and protein level of IRG1 was extremely slight in PMA-induced THP-1 cells (macrophages) and PMA did not affect the expression of IRG1 (Fig. S1A).Consistent with previous reports, IRG1 was vigorously upregulated by LPS or IFN-β stimulation (Fig. S1A, B) , .To enhance the expression of IRG1, the flag-tagged … Web9 +Irg1 and neurosupportive C-X-C chemokine receptor 3 Irg1− microglia in vivo (16). Although no mitochondria targeting signal sequence could be identified in the IRG1 amino acid sequence, IRG1 protein has been reported to associate with mitochondria (6). Taken together, these data indicate an important role of Irg1 during immune response. howard peace
Immune Responsive Gene 1 (IRG1) Promotes …
WebInternal Revenue Service • • • • • instructions. WebPolyclonal Antibody for studying IRG1 mouse. Cited in 2 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, IRG1 Antibody (CST #17805) … WebForm CT-1 is used to report taxes imposed by the Railroad Retirement Tax Act (RRTA). Use Form CT-1 to report taxes imposed by the Railroad Retirement Tax Act (RRTA). how many kids does ben smallbone have