Web15 okt. 2024 · Data from our study suggest that metformin enhanced the anti-tumour effect of cisplatin on epithelial ovarian cancer in vitro and in vivo, which provides more evidence supporting the use of metformin to treat epithelial ovarian cancer. Keywords: TGFβ, metformin, epithelial ovarian cancer, cisplatin, metastasis Introduction Web21 nov. 2024 · Taken together, our observations suggest that metformin inhibits the inflammatory pathway induced by paclitaxel and cisplatin treatment. Furthermore, metformin in combination with paclitaxel or cisplatin improved the sensitivity in drug-resistant ovarian cancer cells.
Frontiers Metformin-induced AMPK activation promotes cisplatin ...
Web10 apr. 2024 · Systemic therapy is considered standard of care for previously untreated BTC and often includes gemcitabine and cisplatin chemotherapy as established by the phase III ABC-02 trial. 7 A phase III randomized trial, S1815 that explored the potential benefit of the addition of nab-paclitaxel to gemcitabine and cisplatin 8 reported no additional benefit in … Web31 mrt. 2024 · Maisto SA, Krenek M, Chung T, Martin CS, Clark D, Cornelius J. A comparison of the concurrent and predictive validity of three measures of readiness to change alcohol use in a clinical sample of adolescents. Psychol Assess. 2011 Dec;23(4):983-94. doi: 10.1037/a0024136. Epub 2011 Jul 18. internist salary range
Metformin enhances the radiosensitizing effect of cisplatin in …
Web11 apr. 2024 · Cisplatin is a widely used chemotherapeutic agent for treatment of various cancers. However, treatment with cisplatin is associated with drug resistance and several adverse side effects such as nephrotoxicity, reduced immunity towards infections and … Web29 nov. 2024 · Metformin Treatment Sensitizes A375 Cells to Cisplatin via Blocking Exosomal Secretion of miR-34a Metformin is recently found to increase the sensitivity of cancer cells to chemotherapy. Then, the role of metformin in sensitizing A375 cell to cisplatin was further investigated. Webfrom publication: Metformin potentiates rapamycin and cisplatin in gastric cancer in mice Here we showed that pAMPKα and PTEN were down-regulated and p-mTOR, p-S6, p-4EBP1, ... internist salary ontario