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Phospho stat1

WebMar 31, 2024 · STAT1 is localized predominantly in the cytoplasm prior to cytokine stimulation and upon receptor activation by IFNγ, the receptor-associated JAKs phosphorylate a critical tyrosine residue at position 701 in the STAT1 transactivation domain producing phosphorylated STAT1 (P-STAT1). WebNov 29, 2024 · IFN-I is the key regulatory component activating and modulating the response of innate and adaptive immune system to bacterial as well as viral pathogens. IFN-I promotes the expression of IFN-induced genes (ISG) and, consequently, the production of chemokines, e.g., CXCL10. Those chemokines control migration and localization of …

Recombinant Anti-STAT1 (phospho S727) antibody …

WebMar 21, 2024 · STAT1 (Signal Transducer And Activator Of Transcription 1) is a Protein Coding gene. Diseases associated with STAT1 include Immunodeficiency 31C and Immunodeficiency 31B . Among its related pathways are IL-9 Signaling Pathways and Prolactin Signaling . Gene Ontology (GO) annotations related to this gene include DNA … WebAnti-phospho-STAT1 (Tyr701) Antibody is a Rabbit Polyclonal Antibody for detection of phospho-STAT1 (Tyr701) also known as Transcription factor ISGF-3 components p91/p84 & has been validated in WB. Research Category Epigenetics & Nuclear Function. Research Sub Category Transcription Factors. china machine clean face https://hitechconnection.net

IJMS Free Full-Text IFNβ-Induced CXCL10 Chemokine …

WebSTAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism. Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure. The STAT1 gene is located on chromosome 2. WebSTAT1 Phospho (Tyr701) A17012A : ICFC, ICC, WB, ChIP: STAT1 Phospho (Ser727) A15158B : ICFC, ICC, WB, ChIP: STAT3 Phospho (Ser727) A16089B : ICFC, WB, ChIP: Need a control for your phospho flow cytometry staining? Our Veri-Cells™ Phospho PBMCs can be used as a positive and negative control for staining members of the MAPK/ERK pathway. WebInvitrogen Anti-Phospho-STAT1 (Tyr701) Polyclonal, Catalog # 44-376G. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF), Immunohistochemistry (Paraffin) (IHC (P)) and … china machined metal parts price

Phospho-Stat1 (Tyr701) (58D6) Rabbit mAb - Cell …

Category:Phospho‑STAT1 expression as a potential biomarker for …

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Phospho stat1

Phospho-Stat Antibody Sampler Kit Cell Signaling Technology

WebWestern blot analysis of extracts from HeLa, A20, and PC-12 cells, untreated or treated with Human Interferon-α1 (hIFN-α1) #8927 (10 ng/ml, 30 min), using Phospho-Stat1 (Tyr701) (D4A7) Rabbit mAb (upper) or Stat1 Antibody #9172 (lower). WebSTAT1, also known as signal transduction and activator of transcription 1, is a ubiquitously expressed cytoplasmic protein and is activated in response to cytokine signaling, including IFN-α, IFN-γ, EGF, PDGF, and IL-6. Upon activation, STAT1 is phosphorylated at Tyrosine 701 (Tyr701) by receptor-associated kinases, including JAK1, JAK2, and ...

Phospho stat1

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WebMar 31, 2024 · Our data demonstrate a novel role of U-STAT1 in affecting nuclear accumulation of P-STAT1, such that a high intracellular concentration of U-STAT1 inhibits … WebAug 15, 2024 · Membranes were then incubated overnight at 4°C with primary antibodies specific for p65, IκBα, IKKβ, phospho-IKKβ (Abcam, Cambridge, UK), phospho-Stat1 (Santa Cruz, Dallas, TX), Stat1 (ThermoFisher, Wilmington, DE), or actin (LI-COR Biosciences, Lincoln, NE) at recommended dilutions. Membranes were washed and subsequently …

WebThe Cell-Based phospho-STAT1 (pTyr701) ELISA kit is a very rapid, convenient, and sensitive assay kit that can monitor the activation or function of important biological pathways in cells. It can be used for measuring the relative amount … WebSTAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus …

WebThe level of phospho‐STAT1 was compared to that from alloantigen‐primed or naïve CD4 + CD25 + T cells. The active forms of both STAT1α (91KD) and STAT1β (84KD) could be detected by anti‐phospho‐STAT1 (Tyr701) in CD4 + CD25 + T cells, with STAT1α present at a higher concentration compared with STAT1β (Figure 1B, upper panel). WebSee all STAT1 primary antibodies Description Mouse monoclonal [M135] to STAT1 (phospho Y701) Host species Mouse Specificity The antibody detects 84 and 91 kDa …

WebInvitrogen Anti-Phospho-STAT1 (Tyr701) Monoclonal (ST1P-11A5), Catalog # 33-3400. Tested in Western Blot (WB), Immunohistochemistry (Paraffin) (IHC (P)), ChIP assay … china machine hotter than sunWebAug 15, 2024 · Membranes were then incubated overnight at 4°C with primary antibodies specific for p65, IκBα, IKKβ, phospho-IKKβ (Abcam, Cambridge, UK), phospho-Stat1 … china machine injectionWebJan 28, 2024 · STAT1,货号：Thermo Pierce MA119323,规格：100 µg Phospho-STAT1 pSer727,货号：Thermo Pierce MA119325,规格：100 µg NTAL,货号：Thermo Pierce MA119327,规格：100 µg NTAL,货号：Thermo Pierce MA119329,规格：100 µg Fyn,货号：Thermo Pierce MA119331,规格：100 µg grain-fed vs grass-fed beef tasteWebJun 28, 2024 · p-Stat1 Antibody (A-2) is an IgG1 κ mouse monoclonal p-Stat1 antibody suitable for the detection of Stat1 phosphorylated at Tyr 701 of mouse, rat and human origin by WB, IP, IF, FCM and ELISA. p-Stat1 Antibody (A-2) is available as the non-conjugated anti-p-Stat1 antibody form, as well as multiple conjugated forms of anti-p-Stat1 … china machine new energyWebSTAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism. Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure. The STAT1 gene is located on chromosome 2. grain feed hayWebPhospho-STAT1 regulates pro- and anti-apoptotic genes following several stress-induced responses. It interacts with p53 and promotes p53-mediated transcriptional gene activity and apoptosis. STAT1 is also an essential factor of stress-induced and DNA damage-induced checkpoint pathways and thus, acts as a tumor suppressor. 1 4 2. china machine press book collectionWebSTAT1, also known as signal transduction and activator of transcription 1, is a ubiquitously expressed cytoplasmic protein and is activated in response to cytokine signaling, including IFN-α, IFN-γ, EGF, PDGF, and IL-6. china machine new energy corporation