Population genomics from pool sequencing
WebNext generation sequencing of pooled samples is an effective approach for studies of variability and differentiation in populations. In this paper we provide a comprehensive set of estimators of the most common statistics in population genetics based on the frequency spectrum, namely the Watterson estimator , nucleotide pairwise diversity Π, Tajima's D, Fu … WebPopulation genomics is a fast-developing discipline with promising applications in a growing number of life sciences fields. Advances in sequencing technologies and bioinformatics …
Population genomics from pool sequencing
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WebNov 7, 2013 · Sequencing of pooled samples (Pool-Seq) using next-generation sequencing technologies has become increasingly popular, because it represents a rapid and cost-effective method to determine allele frequencies for single nucleotide polymorphisms (SNPs) in population pools. Validation of allele frequencies determined by Pool-Seq has …
WebJul 12, 2024 · Low-coverage whole genome sequencing (lcWGS) has emerged as a powerful and cost-effective approach for population genomic studies in both model and nonmodel species. However, with read depths too low to confidently call individual genotypes, lcWGS requires specialized analysis tools that explicitly account for genotype uncertainty. WebAug 11, 2024 · Because of new high throughput sequencing technologies and the availability of a whole genome sequence assembly for goldfish , we implemented both reduced representation (i.e., Restriction-site associated DNA sequencing (RAD-seq) [27, 28], and whole genome (i.e., Pool sequencing (Pool-seq) [29, 30]) approaches to identify sex-linked …
WebSep 23, 2014 · Sequencing the entire genome using Pool-seq, rather than pre-defined regions, is an unbiased approach that allows the discovery of functional differences in the absence of a well-defined genomic ... WebNov 2, 2024 · Functions for the computation of f- and D-statistics (estimation of 'Fst', Patterson's 'F2', 'F3', 'F3*', 'F4' and D parameters) in population genomics studies from allele count or Pool-Seq read count data and for the fitting, building and visualization of admixture graphs. The package also includes several utilities to manipulate Pool-Seq data stored in …
WebAug 2, 2016 · The performance of PoPoolationTE2 for Pool-Seq data from a single population is similar to other tools dedicated to TE analysis in pooled samples (TEMP [Zhuang et al. 2014], PoPoolationTE [Kofler et al. 2012], table 2).PoPoolationTE2, however, required the least computation time which facilitates the analysis of multiple samples.
Web16 hours ago · Short reads are commonly used in large population genomics studies, ... M. et al. High-coverage whole-genome sequencing of the expanded 1000 Genomes Project … graphite series 760tWebOct 28, 2013 · This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our … graphite seed flow lubricantWebApr 30, 2014 · Although pooled-population sequencing has become a widely used approach for estimating allele frequencies, ... Ferretti L, Ramos-Onsins SE, Pérez-Enciso M. Population genomics from pool sequencing. Mol Ecol. 2013; 22:5561–5576. [Google Scholar] Futschik A, Schlötterer C. graphite sectional sofaWebApr 10, 2024 · In fact, numerous whole-genome sequencing studies have been published since, studying honey bee population structure and diversity 4,5,6,7,8, evolutionary history 9,10, and investigating ... chisholm bailWeb18 minutes ago · Large-scale biodiversity genomics projects that take advantage of the latest developments in long-read sequencing technologies offer a valuable source of information. We here present a comprehensive, reference-free, whole-genome, multiple sequence alignment of 88 species of Lepidoptera. graphite serwisWeb1 day ago · We sequenced and published in the journal Science in 2010, for the first time, a whole human genome for $5,000, a 10-fold improvement, using patterned DNA arrays of DNA nanoballs, a much more ... chisholm bachelor of nursingWebWhile the characterization of genetic structure from individual sequencing data remains expensive for many nonmodel species, it has been shown that sequencing pools of … chisholm bakery