WebJun 24, 1997 · c-myc is an early serum response gene whose deregulated expression is the molecular signature of Burkitt lymphomas and is frequently found in various human and animal tumors (16–19).The c-Myc protein participates in the regulation of cell proliferation, differentiation, and apoptosis (20, 21). c-Myc is a basic helix–loop–helix (HLH)/leucine … Webc-Myc (also known as Myc), together with l-Myc and n-Myc, belongs to the Myc family of transcription factors. c-Myc has a basic helix-loop-helix leucine zipper domain and through heterodimerization can bind and regulate the transcriptional activity of genes, either by repression or activation. It is a key player in the regulation of cell growth ...
THE™ c-Myc Antibody [HRP], mAb, Mouse - GenScript
WebMar 15, 2024 · Lineage. Also known as. MRTL; MYCC; c-Myc; bHLHe39. Summary. This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. WebManage clinic visit with Health Buddy app. Your health is in your hands. Access health information & services anytime, anywhere. Locate nearest Singhealth Hospitals, Specialty Centres and Polyclinics. Find a GP near you! Register as authorised caregiver to manage your loved one's SingHealth matters. Follow your 'Care Plan' to guide your through ... most popular video editing tools
IJMS Free Full-Text The Role of Glycogen Synthase Kinase-3 in …
WebThe constitutive and dysregulated expression of the transcription factor MYCN has a central role in the pathogenesis of the paediatric brain tumour medulloblastoma, with an increased expression of this oncogene correlating with a worse prognosis. Consequently, the genomic and functional alterations of MYCN represent a major therapeutic target to attenuate … WebIn vivo screening identifies SPP2, a secreted factor that negatively regulates liver regeneration. Hepatology. 2024 Apr 12. doi: 10.1097/HEP.0000000000000402. Online ahead of print. WebJan 30, 2024 · Elevated expression of CD47 in some cancers is associated with poor survival related to its function as an innate immune checkpoint when expressed on tumor cells. In contrast, elevated CD47 expression in cutaneous melanomas is associated with improved survival. Previous studies implicated protective functions of CD47 expressed by immune … mini high waisted party skirt